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Enzyme-powered spray zaps pet stains & odors, CRI-certified and safe around kids and pets—works on carpets, furniture and other pet spaces.
$23.92 on Amazon
Buy NowPrice and availability are accurate as of 10/27/2025 07:24 pm GMT and are subject to change.
Living with pets brings immeasurable joy, but it also comes with a challenge many pet parents know all too well – persistent odors that seem impossible to eliminate. Whether it’s that lingering “wet dog” smell, stubborn urine accidents, or just the general mustiness that comes with sharing your space with furry friends, finding an effective pet odor eliminator can make all the difference in maintaining a fresh, welcoming home.
I’ve spent years testing various products and consulting with veterinarians and cleaning experts to identify truly effective solutions. In this comprehensive guide, I’ll share the 10 best pet odor eliminators for 2025 that actually work – not just mask odors temporarily but eliminate them at the source. From enzymatic sprays to whole-room treatments, I’ve found options for every pet odor challenge you might face.
Quick Comparison: Best Pet Odor Eliminators for Home 2025
| Product | Key Features | Coverage Area | Price Range | Rating |
| Rocco & Roxie Professional Strength Stain & Odor Eliminator | Enzymatic formula, chlorine-free, color-safe | Up to 500 sq ft | $$$ | 4.8/5 |
| Nature’s Miracle Advanced Stain & Odor Eliminator | Bio-enzymatic formula, works on set-in stains | Up to 300 sq ft | $$ | 4.6/5 |
| Angry Orange Pet Odor Eliminator | Citrus-based, commercial strength | Up to 400 sq ft | $$ | 4.5/5 |
| Bissell Professional Pet Stain & Odor Remover | Pro-level formula, works on multiple surfaces | Up to 250 sq ft | $$ | 4.7/5 |
| Lively Pet Multi-Surface Stain & Odor Remover | Probiotic formula, works for up to 3 days | Up to 300 sq ft | $$ | 4.7/5 |
| Simple Solution Extreme Pet Stain & Odor Remover | 3-in-1 nozzle, pro-bacteria formula | Up to 200 sq ft | $$ | 4.4/5 |
| Biokleen Bac-Out Enzyme Stain & Odor Remover | Plant-based, biodegradable, lime scent | Up to 350 sq ft | $$$ | 4.5/5 |
| Arm & Hammer Pet Stain & Odor Eliminator | Baking soda formula, OxiClean technology | Up to 200 sq ft | $ | 4.3/5 |
| Zep Air & Fabric Odor Eliminator | Professional-grade, long-lasting fragrance | Up to 300 sq ft | $ | 4.2/5 |
| Febreze FABRIC Pet Odor Fighter | Fabric refresher, odor neutralizing | Up to 150 sq ft | $ | 4.0/5 |
1. Rocco & Roxie Professional Strength Stain & Odor Eliminator
When it comes to tackling the toughest pet odors and stains, Rocco & Roxie Professional Strength Stain & Odor Eliminator consistently outperforms the competition. This enzymatic cleaner has earned its reputation as the gold standard for pet messes, with over 118,000 positive reviews on Amazon alone.
What sets this formula apart is its chlorine-free, color-safe enzymatic formula that works by actually breaking down the organic matter causing odors rather than just masking them. The enzymes continue working until all the odor-causing bacteria are completely eliminated, making it especially effective for stubborn urine odors that seem impossible to remove.
Pros
- Certified safe for all carpets by the Carpet and Rug Institute
- Works on multiple surfaces including carpets, furniture, and hard floors
- Effective on old, set-in stains and odors
- Safe around pets and children when used as directed
- Fast-acting formula shows results in as little as 10 minutes
Cons
- Higher price point than some competitors
- Unscented formula (some users prefer a fragrance)
- May require multiple applications for severe cases
Specifications
| Enzymatic spray | 32 oz |
| Unscented | Carpets, upholstery, pet bedding, clothing, floors |
| 10-15 minutes | Yes |
“After trying countless products, this finally eliminated the cat urine smell completely from our basement carpet. One application and the odor was gone for good!”
2. Nature’s Miracle Advanced Stain & Odor Eliminator
Nature’s Miracle has been a trusted name in pet stain and odor removal for decades, and their Advanced formula represents the culmination of their expertise. This bio-enzymatic formula is particularly effective at tackling set-in stains and persistent odors that other cleaners can’t touch.
What makes this product stand out is its ability to work on old, dried stains that have had time to penetrate deep into carpet fibers and padding. The enzymes continue working for up to 24 hours after application, breaking down even the most stubborn odor sources at the molecular level.
Pros
- Excellent value for the size and effectiveness
- Pleasant citrus scent that doesn’t just mask odors
- Works on both fresh accidents and set-in stains
- Safe for use on multiple surfaces including carpets and upholstery
- Discourages remarking by pets
Cons
- Requires longer dwell time (up to 12 hours for set-in stains)
- Citrus scent may be too strong for some users
- May require covering treated area with cloth for best results
Specifications
| Bio-enzymatic spray | 24 oz |
| Citrus | Carpets, upholstery, hard floors, pet bedding |
| 10 min (fresh) to 12 hrs (set-in) | Yes (when dry) |
“This is the only product that completely eliminated the cat urine smell from our couch. We tried everything else with no success. Nature’s Miracle truly lives up to its name!”
3. Angry Orange Pet Odor Eliminator
If you’re tired of pet odor eliminators that leave behind a chemical smell, Angry Orange offers a refreshing alternative. Originally developed for commercial use on farms, this powerful formula uses cold-pressed orange oil to deliver a pleasant citrus scent while effectively eliminating even the strongest pet odors.
What makes Angry Orange unique is its dual-action approach – it doesn’t just mask odors with fragrance, but actually uses citrus enzymes to break down odor molecules at the source. The result is a genuinely fresh-smelling home, not just one where pet odors are covered up by artificial scents.
Pros
- Powerful commercial-grade formula
- Natural orange oil provides pleasant, long-lasting scent
- Works on multiple surfaces including carpet, turf, and concrete
- Highly concentrated formula can be diluted for different uses
- Effective on strong odors like cat urine
Cons
- Orange scent may be too strong for some users
- Higher price point than some competitors
- Not as effective on old, set-in stains
Specifications
| Citrus enzyme spray | 32 oz |
| Orange twist | Carpets, hard floors, turf, concrete, upholstery |
| 5-10 minutes | Yes (when dry) |
“The smell is amazing! Not only did it eliminate the pet odors completely, but my whole house smells like fresh oranges. This is the only cleaner I’ll use from now on.”
4. Bissell Professional Pet Stain & Odor Remover
Bissell is a trusted name in floor care, and their Professional Pet Stain & Odor Remover brings that expertise to tackling pet messes. This formula stands out for its exceptional versatility – it works effectively on carpets, upholstery, mattresses, and even removes food stains.
What makes this product special is its continuous action formula. Unlike cleaners that stop working after application, Bissell’s enzymes keep working for up to 72 hours, gradually breaking down odor sources at the molecular level. This makes it particularly effective for deep-set odors that have penetrated carpet padding.
Pros
- Works on virtually any surface that can be safely cleaned with water
- Effective on both pet messes and food stains
- Unscented formula won’t clash with home fragrances
- Continues working for up to 72 hours after application
- Prevents pets from remarking the same area
Cons
- Requires significant dwell time for best results
- May need to cover treated area with damp cloth
- Unscented (some users prefer a fragrance)
Specifications
| Enzymatic spray | 22 oz |
| Unscented | Carpets, upholstery, mattresses, hard surfaces |
| 12-72 hours for deep odors | Yes |
“I’ve tried everything to get rid of the dog urine smell in our carpet. This is the only product that completely eliminated it. It takes time to work, but the results are worth the wait!”
5. Lively Pet Multi-Surface Stain & Odor Remover
Lively Pet Multi-Surface Stain & Odor Remover takes a unique approach to pet messes with its probiotic-powered formula. Instead of traditional enzymes, it uses beneficial bacteria that continue eating away at odor-causing compounds for up to 3 days after application.
What sets this product apart is its ability to work at the microscopic level, breaking down organic matter completely rather than just treating the surface. This makes it particularly effective for areas with recurring pet accidents or deep-set odors that other cleaners can’t reach.
Pros
- Continues working for up to 3 days after application
- pH-neutral formula safe for all colorfast surfaces
- No harsh chemicals or overwhelming fragrances
- Works on both hard surfaces and fabrics
- Prevents odor recurrence by eliminating source bacteria
Cons
- No foaming action (may seem less effective to some users)
- Unscented (some users prefer a fragrance)
- Slightly higher price point
Specifications
| Probiotic spray | 16 oz |
| Unscented | Sealed floors, carpet, furniture, pet bedding, crates |
| Works for up to 3 days | Yes |
“This is the only cleaner that permanently removed the cat urine smell from our sofa. Other products worked temporarily, but the smell would return. With Lively, it’s completely gone!”
6. Simple Solution Extreme Pet Stain & Odor Remover
Simple Solution Extreme Pet Stain & Odor Remover excels at tackling fresh pet accidents quickly and effectively. Its standout feature is the innovative 3-in-1 nozzle that lets you choose between foam, mist, or stream applications depending on the surface and stain type.
What makes this product particularly useful is its fast-acting formula that begins working in just five minutes. For busy pet parents who need to clean up accidents quickly, this provides a significant advantage over products that require longer dwell times.
Pros
- Versatile 3-in-1 nozzle for different application needs
- Fast-acting formula works in as little as 5 minutes
- Effective on both soft and hard surfaces
- Pro-bacteria formula continues working until dry
- Good value for the size
Cons
- Some users report a strong chemical scent
- Not as effective on old, set-in stains
- May require multiple applications for severe odors
Specifications
| Pro-bacteria spray | 32 oz |
| Light chemical scent | Carpets, upholstery, hard surfaces, pet crates |
| 5 minutes to dry | Yes (when dry) |
“The 3-in-1 sprayer is genius! I use the foam setting for our couch and the stream for carpet. It works quickly and doesn’t leave any residue. Perfect for homes with puppies!”
7. Biokleen Bac-Out Enzyme Stain & Odor Remover
For environmentally conscious pet owners, Biokleen Bac-Out offers an effective solution without harsh chemicals. This fully biodegradable formula is made in the USA from plant-based ingredients, making it one of the most eco-friendly options available.
What makes this product special is its versatility beyond just pet messes. The live enzyme cultures work on everything from pet accidents to wine spills, urine-soaked cloth diapers, and even garbage cans. The pleasant lime scent comes from natural sources rather than artificial fragrances.
Pros
- Fully biodegradable, plant-based formula
- No artificial fragrances, dyes, or phosphates
- Pleasant natural lime scent
- Excellent value in gallon size
- Made in the USA
Cons
- Liquid format less convenient than spray bottles
- May need to purchase separate spray bottle
- Not as effective on very old stains
Specifications
| Liquid enzyme cleaner | 128 oz (gallon) |
| Lime essence | Carpets, upholstery, laundry, hard surfaces |
| 10-15 minutes | Yes |
“I love that this is plant-based and actually works! The gallon size is a great value, and I use it for everything from pet accidents to laundry. The lime scent is refreshing without being overwhelming.”
8. Arm & Hammer Pet Stain & Odor Eliminator
Arm & Hammer brings their trusted baking soda technology to pet odor elimination with this budget-friendly option. The formula combines the natural deodorizing power of baking soda with OxiClean stain fighters to tackle both the visible mess and the lingering smell.
What makes this product stand out in the budget category is its dual-action approach. The baking soda immediately neutralizes odors while the cleaning agents work on removing the stain. For households with multiple pets or those on a budget, this provides excellent value without sacrificing effectiveness.
Pros
- Excellent value for the price
- Combines baking soda and OxiClean technology
- Fresh, clean scent
- Works on both carpets and upholstery
- Readily available in most stores
Cons
- Not as effective on set-in stains
- May require multiple applications
- Abrasive nature could damage delicate fabrics
Specifications
| Baking soda spray | 32 oz |
| Fresh clean | Carpets, upholstery, pet bedding |
| 5-10 minutes | Yes |
“For the price, you can’t beat this cleaner. It works great on fresh pet accidents and leaves a nice clean smell. I keep bottles in multiple rooms for quick cleanups.”
9. Zep Air & Fabric Odor Eliminator
Zep brings professional-grade odor elimination technology to the consumer market with their Air & Fabric Odor Eliminator. This powerful formula is designed to neutralize tough odors in both the air and on fabrics, making it ideal for whole-room freshening.
What sets this product apart is its industrial strength and long-lasting fragrance. While it doesn’t contain enzymes to break down stains, it excels at neutralizing airborne odors and refreshing fabrics that have absorbed pet smells over time. For homes with multiple pets or persistent odor issues, this provides an effective layer of odor control.
Pros
- Professional-grade formula
- Long-lasting fragrance
- Works on both air and fabrics
- Excellent value for the size
- Effectively neutralizes strong odors
Cons
- Not an enzyme cleaner (doesn’t break down stains)
- Fragrance may be too strong for some users
- Primarily neutralizes rather than eliminates odors
Specifications
| Odor neutralizing spray | 32 oz |
| Fresh linen | Carpets, upholstery, clothing, bedding, rugs |
| Immediate | Yes (when dry) |
“This is the strongest odor eliminator I’ve found. We use it in our living room where the dogs hang out, and it keeps everything smelling fresh. The scent is strong but pleasant.”
10. Febreze FABRIC Pet Odor Fighter
Febreze FABRIC Pet Odor Fighter offers a quick and convenient solution for refreshing fabrics between deep cleanings. While it doesn’t contain enzymes to break down stains, it excels at neutralizing odors trapped in fabrics and providing a fresh scent.
What makes this product useful is its versatility and ease of use. It’s perfect for quick refreshes of furniture, curtains, pet bedding, and other fabrics that can’t be easily washed. For homes with pets that love to lounge on furniture, this provides an effective way to maintain freshness between more thorough cleanings.
Pros
- Easy to use with no rinsing required
- Pleasant, long-lasting fragrance
- Safe on most fabrics
- Affordable and widely available
- Works quickly for immediate freshening
Cons
- Only masks odors rather than eliminating them
- No stain-removal properties
- Fragrance may be too strong for sensitive individuals
Specifications
| Fabric refresher spray | 27 oz |
| Fresh scent | Carpets, furniture, upholstery, bedding, toys |
| Immediate | Yes (when dry) |
“I use this daily on our couch where the dogs sleep. It doesn’t remove stains, but it keeps everything smelling fresh between deep cleanings. Great for quick refreshes!”
How to Choose the Best Pet Odor Eliminator for Your Home
With so many options available, selecting the right pet odor eliminator can feel overwhelming. Here are the key factors to consider when making your choice:
Types of Pet Odor Eliminators
Enzymatic Cleaners
These use biological enzymes to break down organic matter like urine, feces, and vomit at the molecular level. They’re the most effective for eliminating odors at the source rather than just masking them.
Oxidizing Cleaners
These use oxygen or hydrogen peroxide to break down odor molecules through chemical reactions. They’re particularly effective for set-in stains and odors.
Neutralizers
These products chemically neutralize odor molecules but don’t necessarily break down the source. They’re good for quick refreshes but may not solve persistent problems.
Masking Agents
These simply cover up odors with stronger, more pleasant scents. They provide temporary relief but don’t address the underlying issue.
Surface Compatibility
Different cleaners are formulated for specific surfaces. Consider where you’ll be using the product most:
- Carpets and rugs require deep-penetrating formulas that won’t damage fibers or backing
- Upholstery needs gentle yet effective cleaners that won’t cause discoloration
- Hard surfaces like tile or hardwood need cleaners that won’t damage finishes
- Multi-surface products offer versatility but may not be specialized enough for tough problems
Odor Source
The type of pet odor you’re dealing with should influence your choice:
- Urine odors require enzymatic cleaners that break down uric acid crystals
- General pet odors (like “wet dog” smell) may respond well to fabric refreshers
- Litter box areas benefit from continuous odor control products
- Set-in odors that have penetrated deeply often need professional-strength solutions
Safety Considerations
Always prioritize the safety of your pets and family:
- Look for non-toxic, pet-safe formulations
- Avoid products containing ammonia, which can attract pets back to the same spot
- Consider fragrance sensitivity for both humans and pets
- Check if the product is safe for the specific type of pet you have (some essential oils can be harmful to cats)
Frequently Asked Questions About Pet Odor Eliminators
What’s the difference between odor eliminators and regular cleaners?
Regular cleaners focus on removing visible dirt and stains but often don’t address the organic compounds causing odors. Pet odor eliminators contain specialized ingredients (like enzymes, oxidizers, or probiotics) that break down these odor-causing compounds at the molecular level. While regular cleaners might mask smells temporarily, odor eliminators work to permanently remove the source of the odor.
Are enzymatic cleaners safe for pets?
Most enzymatic cleaners are formulated to be safe for use around pets when used as directed. The enzymes are naturally occurring proteins that break down organic matter and are typically non-toxic. However, it’s always best to keep pets away from freshly treated areas until the surface is completely dry. Always check the manufacturer’s safety information and follow their specific guidelines.
Why do pet odors come back after cleaning?
Pet odors often return because traditional cleaning methods don’t completely eliminate the source. Urine, for example, contains uric acid crystals that bond to surfaces and can reactivate when exposed to moisture (even humidity in the air). If the cleaning solution doesn’t break down these crystals, the odor will return. Additionally, if urine has soaked through to carpet padding or subfloors, surface cleaning alone won’t reach the source.
How long should I let an enzymatic cleaner sit before wiping it up?
For enzymatic cleaners to work effectively, they need adequate “dwell time” to break down the organic matter. Most manufacturers recommend letting the product sit for at least 10-15 minutes for fresh stains, and up to several hours for set-in odors. Some products even work for days after application. Always follow the specific instructions on your product for best results.
Can I use pet odor eliminators in my carpet cleaning machine?
Some pet odor eliminators are specifically formulated for use in carpet cleaning machines, while others are not. Using the wrong product could damage your machine or reduce its effectiveness. Always check the manufacturer’s instructions before adding any product to your carpet cleaner. Many companies offer specific formulations designed for machine use that will be clearly labeled as such.
Final Thoughts: Finding Your Perfect Pet Odor Solution
Living with pets doesn’t mean living with odors. The right pet odor eliminator can make all the difference in maintaining a fresh, clean home that both you and your furry friends can enjoy.
After extensive testing and research, Rocco & Roxie Professional Strength Stain & Odor Eliminator stands out as our Editor’s Choice for its exceptional performance across multiple surfaces and odor types. Its enzyme-based formula tackles odors at the source rather than just masking them, and its certification from the Carpet and Rug Institute ensures it’s safe for even your most valuable floor coverings.
For those seeking the best value, Nature’s Miracle Advanced Stain & Odor Eliminator offers an excellent balance of performance and price, while Angry Orange provides a refreshing natural scent option that many users prefer over traditional cleaning smells.
Remember that the most effective approach often combines immediate treatment of accidents with regular maintenance cleaning. By addressing pet odors promptly and consistently with the right products, you can enjoy all the love and companionship your pets provide without the unwelcome smells that sometimes come along for the ride.
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Powerful enzyme spray removes pet stains & odors on carpets, furniture and more – gentle, CRI‑approved and safe around kids and pets.
$59.97 on Amazon
Buy NowPrice and availability are accurate as of 10/27/2025 05:14 am GMT and are subject to change.